Advanced joint formula for dogs
A joint-healthy lifestyle supported with a powerful supplement
Building a joint-healthy lifestyle for your dog, starts the very first day you bring your dog home. Finding a veterinarian you trust, a healthy diet your dog loves, and keeping your dog active to maintain a healthy weight all play an important part in proper joint health. Reinforce those efforts with a daily dose of maxxiflex+, a complex joint supplement specifically formulated for dogs to support healthy joint function and alleviate joint pain. Joint discomfort and stiffness may be a part of life, but they do not have to slow your dog down.
Simply our best formulation in every dose
With maxxiflex+ rest assured that we are giving your dog our best science in every dose. From the very beginning we focused on making our joint supplement the right supplement.
Whether you buy directly from us or from one of our retail partners, you are getting the same supplement each and every time, because we know it’s our best.
Our carefully chosen ingredients include potent anti-inflammatory and antioxidants agents. We start with the basic building blocks of proper joint care including glucosamine HCL, chondroitin sulfate, and MSM.
Then we add in an additional layer of our own combination of supporting ingredients that have been shown to support comfortable joint movements, i.e. hyaluronic acid, hydrolyzed collagen, cetylated fatty acids, devils claw, bio active whey protein, and bromelain.
Additionally, we guarantee that all the stated ingredients are present in the product at the date of manufacturing.
Uncompromised quality in every bottle
We make maxxiflex+ with premium quality, human grade, raw materials from trusted suppliers, tested for purity and potency.
We partner with a manufacturer in the United States with more than 50 years of experience in making animal health supplements. Our manufacturer is GMP registered with NSF and an audited member of NASC (National Animal Supplement Council).
And because shelf life has a direct effect on potency, we print the lot number and best by date on every single bottle of maxxiflex+.
Dogs love the taste and their owners love the results
Giving dogs medicine can be a challenge. No pet parent wants to find un-swallowed pills under the couch or have their pet run and hide when it comes to medicine.
Our maxxiflex+ chewable liver-flavored tablets are so delicious they can be given as treats or with the food in their dish.
The tablets are uncoated so it is easy to break them into pieces for smaller doses or crush them into powder if so preferred.
Easy to follow dosage instructions for all weight ranges
maxxiflex+ includes premium ingredients that have been carefully selected for maximum efficiency.
Our simple dosage instructions makes joint care easy for pet owners with multiple dogs, no need to buy for different weight ranges.
Whether the dog you love is happiest walking by your side, running up ahead, or cuddling in for kisses we believe all dogs should move pain-free. Joint discomfort has the potential to impact any dog, regardless of breed, size, shape, or age.
With maxxiflex+ build a joint-healthy lifestyle for your dog before discomfort affects your lives together or help your dog move easier. Together we keep the dog you love on the move.
What is glucosamine?
Glucosamine is a chemical compound that is produced naturally in the body. It’s found in the fluid around the joints and is important building block for cartilage. It helps cartilage to act as a shock absorber.
Glucosamine comes in different forms, most commonly as glucosamine hydrochloride (HCL / HCl), glucosamine sulfate, and n-acetyl-glucosamine. The first two forms are most commonly used as canine glucosamine but glucosamine HCL is the highest quality, purest form of glucosamine.
maxxiflex+ contains high strength human grade glucosamine hydrochloride (HCL) for maximum effect.
The benefits of glucosamine for dogs
The cartilage acts as a shock absorber (cushion) for the joints, i.e. provides smooth surface between the bones to eliminate painful bone-on-bone contact. Over time, normal wear and tear can erode the cartilage, causing joint pain and inflammation.
Dogs with arthritis (estimated around 20% of dogs) suffer most as the cartilage can degrade to the point that the bones come into contact with each other. This is very painful and can seriously limit the dog’s movements.
Glucosamine is the key building block for making cartilage and taking glucosamine supplement may help to supply the materials needed to rebuild the cartilage.
Other benefits of glucosamine include anti-inflammatory effects, as it may prevent swelling and inflammation in the joints (common in dogs with arthritis).
“Glucosamine hydrochloride (HCl) and glucosamine sulfate both work equally well in the cat and dog. The sulfate form was originally used in Europe. The HCl form has recently become more popular because it is purer and provides more available glucosamine per unit weight and contains much less residual ash” (MedicAnimal)
The source of glucosamine for dogs
There aren’t any natural food sources of glucosamine. Glucosamine supplements are derived from chitin, substance found in the shells of shrimps, lobsters, and crabs. It can also be made in a laboratory.
The glucosamine in maxxiflex+ comes from shellfish source.
What is chondroitin?
Chondroitin sulfate is the major glycosaminoglycan (group of compounds) found in cartilage. Chondroitin attracts fluid inside the joints, helping to ensure adequate shock absorption and nourishment of the tissues that line the joint.
Glucosamine and chondroitin for dogs are frequently used together as they are considered to improve each substance's beneficial effects. maxxiflex+ contains high strength human grade chondroitin sulfate combined with glucosamine HCL.
The benefits of chondroitin for dogs
Like glucosamine, chondroitin for dogs may inhibit the production of inflammatory mediators that are destructive to the joint.
The body's chondroitin production decreases with age. Joint supplement with chondroitin are therefore considered especially helpful for older dogs with arthritis.
"Chondroitin sulfate may actually help the body to repair damaged cartilage and help restore joint integrity. It may also protect existing cartilage from premature breakdown as well as keep cartilage tissue hydrated and assist in cushioning impact stress" (petMD)
What is hydrolyzed collagen?
Collagen is the main structural component of connective tissue (cartilage, ligaments, tendons, bones, skin). It helps the connective tissue to withstand great force without breaking down or tearing. Collagen is the most abundant protein in mammals (25-30%) but the body's ability to produce and maintain collagen progressively declines after we reach adulthood.
Hydrolyzed collagen is a modified form of collagen that is easier for the body to digest and absorb. It is composed of small amino acids (derived from bovine bone and cartilage) and helps to form new collagen in the body.
The benefits of hydrolyzed collagen
There are various claims about the health benefits of hydrolyzed collagen.
What matters for dogs joint health is its potential ability to protect (and even increase) lean muscle mass and to help improve the symptoms of arthritis.
There are number of human clinical studies available confirming that hydrolyzed collagen can be beneficial for joint health. For example this study that concludes that “hydrolyzed collagen has a positive therapeutic effect on osteoporosis and osteoarthritis with a potential increase in bone mineral density, a protective effect on articular cartilage, and especially in the symptomatic relief of pain” (Scielo)
As well as this one showing that there “was a significant improvement in knee joint comfort as assessed by visual analogue scales to assess pain and the Womac pain subscale” (Taylor & Francis Online)
What is MSM?
Methylsulfonylmethane (MSM) is a naturally occurring sulfur (sulphur) compound found in the body.
MSM is the source of sulfur in the body but sulfur is essential chemical needed for the synthesis of cartilage.
MSM is found in variety of foods, like meat, fish, eggs, milk and to a lesser amount in fruits and vegetables. Some MSM is lost during storage and food preparation and the amount of MSM decreases with age, meaning supplementing MSM may be required.
The benefits of MSM for dogs
The cartilage in a dog with arthritis has about one third of the concentration of sulfur when compared to healthy cartilage.
MSM is therefore highly beneficial for arthritic dogs as it provides sulfur used by the cartilage in the healing process. It may have anti-inflammatory benefits as well.
Laboratory studies on humans have found that “MSM has anti-inflammatory and antioxidant effects. Sulphur, which is a major component of MSM, plays an important role in making collagen and glucosamine, both of which are vital for healthy bones and joints, and in the production of immunoglobulins, which help your immune system” (Arthritis Research UK)
What is fructooligosaccharides?
Fructooligosaccharides (FOS) are made up of plant sugars (fructose) that are linked together in chains.
FOS is found naturally in asparagus, onions, banana, wheat, garlic, soybeans, artichoke, tomatoes and other fruits, vegetables and grains. It can also be manufactured in laboratories.
The benefits of fructooligosaccharides
Fructooligosaccharides are best known for stimulating beneficial flora growth in the digestive tract, i.e. acting as a prebiotic.
Studies have shown that FOS is also ideal for maintaining mineral density and bone strength. It increases mineral content in the bones and supports joint health, i.e. through better absorption of calcium, magnesium, and iron.
What is bio active whey?
Whey protein is a mix of globular proteins that are isolated from whey (the liquid by-product of cheese production).
The benefits of bio active whey
Bio Active Whey protein supports joint health by balancing immune and gut function.
Some preclinical studies in rodents have suggested that whey protein may possess anti-inflammatory properties as well (Wikipedia).
What is devil's claw?
Devil's claw is herb, native to southern Africa. It contains iridoid glycosides, components that are believed to have strong anti-inflammatory effects.
The benefits of devil's claw for dogs
Devil's claw has a very long history of use as an anti-inflammatory and modern research has confirmed its effectiveness. Actually few joint supplement ingredients have been shown to be as effective as devil's claw.
Today, devil's claw is widely used to fight inflammation or relieve pain in arthritis in both humans and animals.
Devil's claw has repeatedly shown to be statistically significant in reducing pain experienced by people with osteoarthritis. Most animal studies also support the anti-inflammatory and analgesic effects of devil's claw extracts.
Recent scientific article found that results of couple of high-quality trials suggest that devil’s claw is effective in the reduction of osteoarthritis-related symptom (Arthritis Research UK)
What is phellodendron tree extract?
Phellodendron is a plant which bark has been used in medicine to treat various health problems, including osteoarthritis.
The benefits of phellodendron tree extract
Some chemicals in phellodendron may reduce redness and swelling (inflammation).
There is available study that shows that Phellodendron combined with Citrus sinensis peel had beneficial effects on symptoms of osteoarthritis of the knee as measured using LAI scores and had anti-inflammatory effects as measured using CRP.
What is cetylated fatty acids?
Cetylated fatty acids (CFA) are a group of naturally occurring fats that support joint and connective tissue health.
The benefits of cetylated fatty acids
Cetylated fatty acids may help lubricate joints and muscles, soften tissues, and increase flexibility. It may also help the immune system and reduce inflammation and swelling,
The exact ways that CFAs work in treating musculoskeletal conditions hasn’t been formally studied. It’s been proposed that they may have a lubricant effect on joints (Arthritis Research UK)
What is DL phenylalanine?
Phenylalanine is an amino acid, a “building block” of protein.
There are three forms of phenylalanine: L-phenylalanine (the natural form found in proteins), D-phenylalanine (a mirror image of L-phenylalanine that is made in a laboratory), and DL-phenylalanine (a 50/50 combination of the other two forms).
The benefits of DL phenylalanine
Phenylalanine has long been used to treat various health problems, including chronic pain, osteoarthritis, and rheumatoid arthritis.
There are insufficient evidences for its efficiency, but it's considered worth including as it may help with chronic pain.
What is bromelain?
Bromelain is an enzyme that occurs naturally in pineapple. As a supplement, it's mainly used to ease pain and swelling.
The benefits of bromelain for dogs
Bromelain is thought to be useful for a variety of conditions. It has been shown to be anti-inflammatory and been used to treat inflammatory conditions like arthritis.
Bromelain seems to cause the body to produce substances that fight pain and swelling (inflammation).
"In recent years, a number of clinical studies have appeared to substantiate one of the traditional therapeutic uses of extracts of bromelain, namely, in the treatment of inflammatory disorders of the musculoskeletal system" (NCBI)
What is calcium ascorbate?
Calcium Ascorbate is a compound made up of ascorbic acid also known as vitamin C and calcium. Calcium Ascorbate is commonly used as an antioxidant, preservative, and source of vitamin C.
The benefits of calcium ascorbate
Calcium supports long-term bone health and vitamin C boosts the immune system.
Taking vitamin C on its own can however deplete the calcium stores in the body, making calcium ascorbate more suitable ingredient in dog joint supplement.
Vitamin C can be helpful in the treatment of different forms of arthritis. It has been shown to improve pain due to gout arthritis because vitamin C reduces the serum level of uric acid.
Other studies show that the ability of vitamin C to reduce the risk of gout and joint pain due to this form of arthritis increases with increasing doses of the vitamin.
Vitamin C can also reduce other kinds of joint pain not associated with arthritis (Progressive Health).
What is hyaluronic acid?
Sodium hyaluronate, also known as hyaluronic acid, is a natural substance found in the body with the highest concentrations in the fluids in the eyes and joints.
The benefits of hyaluronic acid for dogs
Hyaluronic acid works by acting as a cushion (shock absorber) and lubricant in the joints and other tissues.
It gives elasticity to joints, is important for tissue hydration, lubrication and proper cellular function.
The efficacy of oral hyaluronic acid in relieving knee pain has been demonstrated in several clinical trials (NCBI).
What is super oxide dismutase?
Super oxide dismutase (SOD) is an enzyme found in all living cells. An enzyme is a substance that speeds up certain chemical reactions in the body.
The benefits of super oxide dismutase
Super oxide dismutase is an enzyme that helps break down potentially harmful oxygen molecules in cells. This may prevent damage to tissues.
SOD has powerful anti-inflammatory activity. It has been used for the treatment of soft tissue inflammation in horses and dogs, human inflammatory diseases, and chronic bladder inflammations.
Studies indicate that reduction in SOD is associated with the earliest stages of osteoarthritis.
What is turmeric extract?
Turmeric is a plant. It may be best known as the main spice in curry but the root of turmeric is also commonly used to make medicine.
The benefits of turmeric extract for dogs
Whole turmeric possesses anti-inflammatory properties. Much of this observed activity seems to be due to the presence of curcumin, which also acts as a powerful antioxidant.
In animal models, curcurmin has been found to have anti-inflammatory effects in arthritic pets comparable to the NSAID drug Phenylbutazone (The Natural Health Bible for Dogs & Cats by Dr. Shawn Messonnier DVM).
Turmeric extract has very powerful antioxidant effects. The chemicals in turmeric may decrease swelling (inflammation).
Some research has shown that taking turmeric extracts can reduce the pain caused by osteoarthritis of the knee. In one study, turmeric worked about as well as Ibuprofen for reducing pain (WebMD).